Neil Patrick Harris’s most famous role as an adult is that of Barney Stinson, who was a well-known skirt chaser on How I Met Your Mother. In real life, he recently married his husband, David Burtka.
David Hyde Pierce’s most famous TV role was as Niles on Frasier. On that show he chased and eventually landed his father’s live-in physical therapist Daphne. In real life, he chased and eventually married Brian Hargrave.